发明名称 |
Phospholipid derivatives, processes for use thereof and pharmaceutical composition of the same |
摘要 |
New phospholipid derivatives represented by the formula: <IMAGE> (I) wherein R1 is alkyl, alkoxy, alkylthio or alkylsulfonyl; R2 is hydrogen, hydroxy, alkoxy, lower alkanoyloxy or lower alkylcarbamoyloxy; n is 0 or 1; R3 is hydroxy or protected hydroxy; and R4 is lower alkoxy or lower alicyclic-oxy group which is substituted with 2 or more hydroxy or protected hydroxy groups, and may be substituted with lower alkoxy or another alicyclic-oxy group having two or more hydroxy or protected hydroxy groups, in which the alicyclic ring may contain an oxygen atom; and pharmaceutically acceptable salt thereof, which exhibit antitumor activity.
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申请公布号 |
US4585762(A) |
申请公布日期 |
1986.04.29 |
申请号 |
US19830513451 |
申请日期 |
1983.07.13 |
申请人 |
FUJISAWA PHARMACEUTICAL CO., LTD. |
发明人 |
TERAJI, TSUTOMU;TODO, EISHIRO;SHIMAZAKI, NORIHIKO;OKU, TERUO;NAMIKI, TAKAYUKI |
分类号 |
A01N57/12;A61K31/66;A61P35/00;C07D309/12;C07F9/09;C07F9/10;C07F9/117;C07H9/04;C07H11/04;C07H13/04;C07H13/08;(IPC1-7):A61K31/66 |
主分类号 |
A01N57/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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