Granules of thiamine salt and the production thereof.

摘要

57 Granules consisting of a thiamine salt and a binder such as water-soluble celluloses, said thiamine salt accounting for about 95 to about 98 percent by weight on dried basis can be prepared by spray-coating thiamine salt powder at least about 95 percent by weight of which is capable of passing through a 145-mesh sieve with a solution containing a binder while maintaining said thiamine salt powder in a fluidized state in a fluidized-bed granulation apparatus.

The granules are excellent in flowability, mixability, compressibility and bonding properties, and can be used for tablet manufacturing.