摘要 |
(A) Liposomes contg. inhalative allergens or allergen fractions in their aqueous compartments are new. new are medicaments contg. liposomes which incorporate inhalative allergens or allergen fractions. - Pref. liposomes are formed from diacylglycerolethanolamines with 8-24 C-atoms in the aliphatic acyl group and/or lecithins or lecithin derivs. of formula (I): (where R1 is 8-24C aliphatic acyl; R2 is 1-8C alkyl or 8-24C aliphatic acyl; and the groups -OR1, -OR2 and -OPO3CH2CH2N(CH3)s can be exchanged with each other), optionally, in the presence of di(8-24C aliphatic acyl)glycerophosphoric acid esters and/or adjuvant lysolecithins corresponding to formula (I) in which R2 is replaced by H and/or of cholesterols; the aqueous compartment consisting of the allergens or allergen fractions in an isotonic phosphate buffer.
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