摘要 |
This disclosure relates to substituted indolamines, which exhibit anti-diabetic activity, having the formula: <IMAGE> (I) where m is an integer from 1 to 4, x represents hydrogen or -OH R represents Ar or <IMAGE> and Ar represents <IMAGE> <IMAGE> +TR <IMAGE> R1 represents hydrogen, fluoro, chloro, lower alkyl or lower alkoxy, R2 and R3 each, independently, represent lower alkyl, or R2 and R3 together with N represent <IMAGE> wherein n is 1, 2 or 3, R4 represents hydrogen or lower alkyl, and R5 represents hydrogen or lower alkyl, unsubstituted phenyl or phenyl substituted with fluoro, chloro, lower alkyl or lower alkoxy, or or pharmaceutically acceptable acid addition salts thereof.
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