发明名称 2-substituted-3-indolamines and use thereof as anti-diabetics
摘要 This disclosure relates to substituted indolamines, which exhibit anti-diabetic activity, having the formula: <IMAGE> (I) where m is an integer from 1 to 4, x represents hydrogen or -OH R represents Ar or <IMAGE> and Ar represents <IMAGE> <IMAGE> +TR <IMAGE> R1 represents hydrogen, fluoro, chloro, lower alkyl or lower alkoxy, R2 and R3 each, independently, represent lower alkyl, or R2 and R3 together with N represent <IMAGE> wherein n is 1, 2 or 3, R4 represents hydrogen or lower alkyl, and R5 represents hydrogen or lower alkyl, unsubstituted phenyl or phenyl substituted with fluoro, chloro, lower alkyl or lower alkoxy, or or pharmaceutically acceptable acid addition salts thereof.
申请公布号 US4582848(A) 申请公布日期 1986.04.15
申请号 US19830504941 申请日期 1983.06.16
申请人 SANDOZ, INC. 发明人 NADELSON, JEFFREY
分类号 C07D209/14;C07D209/42;C07D413/04;(IPC1-7):A61K31/40;C07D209/12 主分类号 C07D209/14
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