摘要 |
1353520 Veterinary medicines comprising diphenyl sulphones MERCK & CO Inc 13 Sept 1971 [17 Sept 1970 6 July 1971] 42624/71 Heading A5B [Also in Division C2] Compositions, especially suitable for treating or preventing Marek's disease of poultry contain (Ia) (including salts and solvates thereof) as active ingredient Z is a group of formula (I) (or an alkali metal bisulphite or methanol addition product thereof), (II), (III), (IV), (V) (VI), (VII) or VIII where R 1 is a phenyl group optionally substituted with C1, with OH and C 1 to 6 alkoxy, with OH and Cl or with 3, 4-methylenedioxy or is a heterocyclic 5- or 6-membered ring containing one O, N or S hetero atom, R 2 is C 3 to 6 cycloalkyl, CF 3 , C1CH 2 -, NH 2 CH 2 -, 1- amino-2-phenethyl, 2-carboxyethyl, 1-amino-2- carboxyethyl or is a heterocyclic 5- or 6- memibered ring containing one O or N hetero, X and Y are halogen, amino, alkyl or alkoxy and m and n are 0 to 4. Administration is, e.g. orally via feed or drinking water. Other compounding ingredients include, e.g. nutrients such as carbohydrates, proteins, fats, vitamins and minerals as well as, e.g. coccidiostats such as amprolium, ethopabate and nicabazin and 1-(2-n-propyl - 4 - amino-5-pyrimidinylmethyl)- 2-methyl pyridinium chloride hydrochloride. |
申请人 |
MERCK + CO. INC., 126, EAST LINCOLN AVENUE, RAHWAY, N.J. (E.U.A.), |
发明人 |
T.-Y. SHEN;W.V. RUYLE;M.W. FORDICE;N.P. JENSEN. |