| 摘要 |
An improved homogenous binding assay for determining polyvalent analytes employing labeled binding partners for the analyte, such as labeled antibodies. Binding of the labeled binding partner to analyte results in a change in the response from the label due to steric hindrance of access to the label by a member of a reagent detection system which generates the response by interaction with the label. The improvement comprises adding to the system a macromolecular binder selective for binding to analyte, e.g., anti-analyte, whereby the resulting steric hindrance is enhanced. |
