Production of hydroxymethylbutenoic acids via oxidation

摘要

A useful industrial chemical, oxazolinoazetidinylhydroxymethylbutenoic acid derivative (II) can be produced by oxidizing the corresponding oxazolinoazetidinylhalomethylbutenoic acid derivative(I). <IMAGE> wherein R is an alkyl, aralkyl or aryl group, R1 is a hydrogen atom or a carboxy protecting group and Hal is a halogen atom.