| 发明名称 |
PREPARATION OF (THREO)-1-ARYL-2-ACYLAMIDO-3-FLUORO-1- PROPANOLS |
| 摘要 |
A novel sequence of highly selective chemical reactions for conversion of 3-Aryl-2-propyn-1-ols into cis-1-Aryl-3-fluoro-1-propene and into D,L-(threo)-1-Aryl-2-acylamido-3-fluoro-1-propanols is disclosed. Preparation of D-(threo)-1-Aryl-2-acylamido-3-fluoro-1-propanol antibacterial agents including the D-(threo)-3-fluoro-3-deoxy derivatives of chloramphenicol and thiamphenicol is also disclosed. |
| 申请公布号 |
AU4809785(A) |
申请公布日期 |
1986.04.08 |
| 申请号 |
AU19850048097 |
申请日期 |
1985.09.17 |
| 申请人 |
SCHERING CORPORATION |
发明人 |
NAGABHUSHAN, TATTANAHALI LAKSHMINARAYAN;MCCOMBIE, STUART WALTER |
| 分类号 |
C07D303/00;C07C231/16;C07C233/18;C07C247/04;C07C255/60;C07C311/15;C07C311/46;C07C311/47;C07C317/32;C07C317/44;C07D209/48;C07D301/14;C07D303/08;C07D303/34 |
主分类号 |
C07D303/00 |
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