| 摘要 |
<p>NEW MATERIAL:A compound of formula I [n is 0, 1; R1 is H, protecting group; R2 is lower hydrocarbon; X is anion; when R3 is -COO<->, m is 0, while m is 1, when R3 is -COOR4(R4 is H, protecting group)] and its salt. EXAMPLE:7beta-Amino-3-(1-methyl-3-pyrrolinium)methyl-3-cephem-4-carbox ylate. USE:An intermediate of antibacterials. PREPARATION:The reaction of a compound of formula II or its salt with another compound of formula III or its salt is carried out in an inert solvent such as acetone, THF or DMF at -10-50 deg.C, when needed, deprotected and the reduction of sulfoxide is effected.</p> |
