摘要 |
Disclosed are novel carbapenem derivatives characterized by a 2-substituent of the formula <IMAGE> wherein A represents C2-C6 straight or branched chain alkylene group and R10 and R11 each independently represents optionally substituted aliphatic, cycloaliphatic, cycloaliphatic-aliphatic, aryl, heterocyclyl, heterocyclyl-aliphatic, heteroaryl or heteroaraliphatic, or R10 and R11 taken together with the S(+) to which they are attached represent an optionally substituted sulfur-containing heterocyclic ring. Such derivatives are useful as potent antibacterial agents. Also disclosed are processes for the preparation of such derivatives. |