| 摘要 |
PURPOSE:Lactic acid and an alcohol are heated in a specific temperature range in the presence of an ion-exchange resin to enable high-yield production of the titled substance which is used in food industry or as an intermediate of medicines or agricultural chemicals easily without trouble of racemization in lactic acid. CONSTITUTION:The objective compound is obtained by reaction between lactic acid and an alcohol in the presence of an ion-exchange resin as a catalyst at 50-170 deg.C, preferably 70-120 deg.C. An alcohol, is cited methanol, ethanol, n- propanol, iso-propanol or n-butanol. The ion-exchange resin is, e.g., H-type strong acid anion-exchange resin, preferably bearing sulfonic acid groups. The form of the resin is, e.g., beads, or fibrils. The amount used is 0.01-1 equivalent, preferably 0.05-0.3 equivalent based on lactic acid. The amount of the alcohol is optimally 2-4 equivalents. |
