2-SUBSTITUTED THIAZOLIDINE, MANUFACTURE AND ANTITUSSIVE AND MUCUS REGULATOR CONTAINING SAME

摘要

2-Substituted thiazolidines compounds having formula I (I) wherein X is a CH2, O or S, R is hydroxy or an acyloxy, alkyloxy, alkenyloxy or alkinyloxy group, R1 is hydrogen or a group of formula R2 is hydrogen or a free or esterified carboxy group, Ra and Rb are hydrogen or methyl, p is zero or 1, R3 is hydrogen, a C1-C2 alkylsulphonyl group, a phenyl or p-Cl phenyl, p-methylsulphonyl group or an acyl group; are useful as mucus regulating, antitussive and antibronchospastic agents.