BENZOFURAN ETHANOLAMINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND THEIR USE IN MEDICINE

摘要

A compound of formula (I): wherein R1 and R2 are hydrogen or methyl, R3 is hydroxy, hydroxyalkoxy, benzyloxy or X-Y-Z wherein (i) X is a bond or oxygen, Y is C1-6 straight or branched alkylene, and Z is hydrogen or carboxy; or (ii) X is a bond or moiety -O-CH2-, Y is C2-6 straight or branched alkenylene, and Z is carboxy; and R4 is an optional substituent, and n is 1, 2 or 3, their esters, amides and salts, are anti-obesity, hypoglycaemic, anti-inflammatory and platelet aggregation inhibiting agents.