发明名称 Novel 5-substituted 2-pyrimidinone nucleosides and methods of use.
摘要 <p>Compounds for inhibiting the replication of DNA viruses which induce the formation of thymidine kinase enzyme of the formula: &lt;CHEM&gt; wherein R1 is a radical selected from the group consisting of chloro, iodo, hydroxy, alkoxyalkyl, hydroxyalkyl, methylamino, formyl, nitro, and unsubstituted hydrocarbon groups of 2 to about 3 carbon atoms or halosubstituted hydrocarbon groups of 1 to about 3 carbon atoms; R2 is hydrogen or hydroxy; and R3 is hydroxy, -OP(O)(OH)2, amino, or -OCOR4 where R4 is alkyl or alkoxyalkyl of 2 to about 18 carbon atoms.</p>
申请公布号 EP0175004(A2) 申请公布日期 1986.03.26
申请号 EP19840110168 申请日期 1984.08.25
申请人 THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK 发明人 BARDOS, THOMAS J.;CHENG, YUNG-CHI;SCHROEDER, ALAN CURTIS;MBUA NGALE EFANGE, SIMON
分类号 C07H19/067;A61K31/70;A61K31/7042;A61K31/7052;A61K31/7064;A61P31/12;C07D239/34;C07D239/36;C07H19/06;C07H19/073;C07H19/16;(IPC1-7):C07H19/06 主分类号 C07H19/067
代理机构 代理人
主权项
地址