SORBITOL, PROCESS FOR ITS PREPARATION, AND USE THEREOF

摘要

"IMPROVED SORBITOL, PROCESS FOR ITS PREPARATION, AND USE THEREOF" A modified sorbitol with improved tableting properties, viz, has a melting point of about 96.degree.C, a bulk density of 0.3 - 0.6 g/ml, a .gamma. -sorbitol content of at least 90%, a purity of at least 98%, a specific surface area of 0.7 - 1.5 m2/g, a bending strength of at least 7 N/mm2 at a compressive force of at least 10,000 N, and a friability of less than 1% at a compressive force of at least 10,000 N, can be prepared by obtaining a sorbitol solution by hydrogenation of crystallized glucose at a temperature below 170.degree.C, and spray-drying this solution at a temperature of 140 to 170.degree.C. The sorbitol thus obtained has a water content of less than 1%. The sorbitol is useful for the production of compressed formulations.