摘要 |
Compounds of formula (I): …<CHEM>… O-C2-6-alkanoyl derivatives thereof and pharmaceutically acceptable salts are described in which X is -S- or -O-, R<1> and R<2> are, each, hydrogen, C1-6-alkyl, allyl, benzyl, phenethyl, methoxyphenethyl or hydroxyphenethyl; and R<3> and R<4> are, each, hydroxy, hydrogen, halo, C1-3-alkyl or C1-3alkoxy. The compounds are dopamine agonists and have antihypertensive activity. Pharmaceutical compositions and methods of use are described, as are processes for their preparation. |