发明名称 1,3-BENZTHIA - OR OXAZOL-2 3H -ONES DERIVATIVES
摘要 Compounds of formula (I): …<CHEM>… O-C2-6-alkanoyl derivatives thereof and pharmaceutically acceptable salts are described in which X is -S- or -O-, R<1> and R<2> are, each, hydrogen, C1-6-alkyl, allyl, benzyl, phenethyl, methoxyphenethyl or hydroxyphenethyl; and R<3> and R<4> are, each, hydroxy, hydrogen, halo, C1-3-alkyl or C1-3alkoxy. The compounds are dopamine agonists and have antihypertensive activity. Pharmaceutical compositions and methods of use are described, as are processes for their preparation.
申请公布号 AU4714385(A) 申请公布日期 1986.03.20
申请号 AU19850047143 申请日期 1985.09.06
申请人 SMITHKLINE BECKMAN CORPORATION 发明人 ORUM DAVID STRINGER;JOSEPH WEINSTOCK
分类号 A61K31/42;A61K31/423;A61K31/425;A61K31/428;A61P9/08;A61P9/10;A61P9/12;C07D263/58;C07D277/68 主分类号 A61K31/42
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