A positive retroregulatory element, plasmid and cells comprising said element and their production, a method of enhancing gene expression using said element and a method of enhancing RNA half life using said element.

摘要

The invention concerns a method for extending the half-life of RNA's. The half-life extension is conferred upon the RNA by a co-transcribed positive retroregulatory element which is ligated to the 3 min end of the DNA sequence coding the RNA. RNAs having an extended half-life conferred by a co-transcribed positive retroregulatory element are also claimed.