| 摘要 |
<p>A hemapheresis system and method comprises a stationary closed housing (12) concentric about a central axis and a feed system that moves blood upwardly from the housing lower end toward an outlet (30) port adjacent a substantially closed upper end. Within the stationary housing (12) is a double walled rotor (14) concentric with the housing (12) and rotatable magnetically within the housing (12) on sealed end bearings. The space between the rotor walls defines a centrifugation gap into which whole blood is passed and within which centrifugal separation takes place as the rotor (14) is spun at a relatively low rate. At the upper end of the rotor (14), lighter matter such as plasma rich in platelets passes continuously inwardly to a central lengthwise passageway (68) leading to an outlet port (24) coaxial with the central axis, while heavier central matter flows through apertures (60) in the outer rotor wall to the upper outlet port (30). In one example the differential impedence is established by housing (12) and rotor (14) configurations which diverge outwardly with compound curvatures, and with space between rotor (14) and housing (12) leading to a closed end. In another example the housing-rotor space is of restricted cross section and an opposing flow of compatible fluid is introduced in an intermediate region of the flow path. These systems are biologically closed and permit continuous return of packed cells to a donor as plasma is collected.</p> |
