摘要 |
<p>5,6-METHANO-5,6-DIHYDRORETINOIDS 5,6-Methano-5,6-dihydroretinoids such as ethyl (E)-5,6-methano-5,6-dihydroretinoate and (E)-1-_ (4-carbethoxyphenyl)-2-methyl-4-(2,2,6-trimethyl-bicyclo¢4.1.0!hept-1-yl)-1,3-butadiene are disclosed. These compounds are useful as chemopreventive agents for inhibiting tumor promotion in epithelial cells and for treating nonmalignant skin disorders.</p> |