TWO-FUNCTIONAL CLONING VECTOR USED IN STRAIN OF STREPTOMYCES

摘要

The invention relates to selectable, recombinant DNA shuttle vectors for use in streptomycetes and E. coli presenting moderately high copy number and comprising: a) an SIMILAR 2.5 kb KpnI origin of replication - containing restriction fragment of plasmid pJL192, and b) one or more DNA segments that convey resistance to at least one antibiotic when transformed into a sensitive restrictionless host cell. <??>The invention further relates to transformants of the aforementioned vectors.