发明名称 |
Antigen derivatives and processes for their preparation |
摘要 |
The invention relates to novel antigen derivatives comprising an antigen and at least one muramylpeptide covalently bonded thereto, if appropriate via a spacer, to pharmaceutical preparations which contain such compounds and to their use as a vaccine. The novel antigen derivatives produce a pronounced increase in the immuno-response to the antigen, and in particular also a cell-medicated immunity under clinically acceptable conditions of administration.
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申请公布号 |
US4574058(A) |
申请公布日期 |
1986.03.04 |
申请号 |
US19830477281 |
申请日期 |
1983.03.21 |
申请人 |
CIBA-GEIGY CORPORATION |
发明人 |
BASCHANG, GERHARD;DIETRICH, FELIX M.;GISLER, ROLAND;HARTMANN, ALBERT;STANEK, JAROSLAV;TARCSAY, LAJOS |
分类号 |
A61K39/00;A61K39/385;C07H9/04;C07H23/00;C07K9/00;(IPC1-7):A61K37/00 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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