| 摘要 |
<p><IMAGE> The compounds I (A1, A2 independently = H, C1-C5hydrocarbon, heterocycle up to 6 ring atoms, carbomonocycle, phenylalkyl, phenylalkenyl; each (except H) unsubstituted or substituted by one or more of F, Cl, CF3, C1-C5alkyl, C1-C5alkoxy, C1-C5alkylthio, di(C1-C5alkyl)-amino, di(C1-C5alkyl)-amino- (C1-C5alkoxy), alpha - or beta -(C1-C5alkoxy)-N-pyrrolidinyl), which are known compounds of interest for their therapeutical activity, principally in the fields of diuresis, lowering of blood pressure, kidney protection and also as antihistaminic agents, are prepared by reacting the corresponding 6-formyl derivatives with 1- dimethylaminomethyl-vinylmagnesium bromide at the boil in a non-polar solvent such as tetrahydrofuran.</p> |
