| 发明名称 |
ALDOL COMPOUNDS, THEIR PRODUCTION AND THEIR USE IN THE PREPARATION OF METHANOPROSTACYCLIN |
| 摘要 |
<p>Aldol derivatives of the formula, …<CHEM>… wherein C = W is a carbonyl group or a protected carbonyl group are intermediates for producing methanoprostacyclin derivatives which are useful medicines for prevention of thrombosis. Such a compound can be produced by cyclizing a dialdehyde compound of the formula …<CHEM>… wherein W is as defined above, preferably in a solvent, with an acid or a base. The dialdehyde (II) can be obtained by oxidation of an olefin.</p> |
| 申请公布号 |
EP0015653(B1) |
申请公布日期 |
1982.01.27 |
| 申请号 |
EP19800300370 |
申请日期 |
1980.02.07 |
| 申请人 |
SUMITOMO CHEMICAL COMPANY, LIMITED |
发明人 |
ONO, KEIICHI;SUGIE, AKIHIKO;KAWAKAMI, HAJIME;KATSUBE, JUNKI |
| 分类号 |
C07C45/00;C07C45/28;C07C45/30;C07C45/40;C07C45/59;C07C45/67;C07C49/523;C07C62/32;C07C67/00;C07C405/00;C07D317/72;C07D319/08;(IPC1-7):07C49/523;07C45/40;07C45/30;07C45/64;07C177/00;07D317/72 |
主分类号 |
C07C45/00 |
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