发明名称 Heterocyclic derivatives
摘要 The invention relates to compounds of the general formula (I) <IMAGE> (I) and physiologically acceptable salts, hydrates and bioprecursors thereof, in which Q represents a benzene ring in which incorporation into the rest of the molecule is through bonds at the 1- and 3- or 1- and 4- positions: Z represents one of the groups <IMAGE> where X represents NCN, NSO2Methyl, NSO2Phenyl or CHNO2. The compounds show pharmacological activity as selective histamine H2-antagonists.
申请公布号 US4571394(A) 申请公布日期 1986.02.18
申请号 US19820401402 申请日期 1982.07.23
申请人 GLAXO GROUP LIMITED 发明人 HAYES, ROGER;BAYS, DAVID E.;MACKINNON, JOHN W. M.
分类号 C07C279/28;C07D239/46;C07D249/14;C07D257/06;C07D295/096;C07D401/06;C07D471/04;(IPC1-7):C07D249/14;A61K31/41 主分类号 C07C279/28
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