| 摘要 |
In order that, in a plaster comprising a composite film having a recess for holding the medicament and having a layer of adhesive surrounding the recess and a composite covering film glued to the recess and covering it, the galenical may be optimized regardless of the properties of a matrix containing the medicament in the recess, it is proposed to close the recess by means of a membrane which is firmly connected to the composite film and is permeable to the active ingredient of the medicament, and to join the composite covering film hermetically to the composite film along a ring extending between the central membrane and the surrounding layer of adhesive. To provide a process for the production of such a plaster in which two separately produced, outer parts of the plaster are joined together in a separable manner by means of an inner layer of adhesive, which process should be capable of rational mass production of the plaster, it is proposed to produce the layer of adhesive as a component of an inner, third part of the plaster, which is produced separately from the two outer parts of the plaster and is subsequently firmly connected to these outer parts. |
