| 摘要 |
PURPOSE:To obtain the titled compound useful as an important intermediate of a hindered piperidine stabilizer, economically, in an industrial scale, at a low cost, by reducing and aminating triacetoneamine with ammonia and hydrogen in the presence of a cobalt-based catalyst at specific temperature and pressure. CONSTITUTION:4-Amino-2,2,6,6-tetramethylpiperidine of formula II is produced by the reductive amination of triacetoneamine of formula I with ammonia and hydrogen. The reaction is carried out at 80-200 deg.C, preferably 100-150 deg.C under a pressure of <150kg/cm<2>G, usually 50-180kg/cm<2>G, in the presence of a cobalt- based catalyst (especially Raney-cobalt). |
