发明名称 Pyrrolidine derivs. prepn.
摘要 <p>The process comprises reaction of a halogenated deriv.. of formula (II) where X is a Cl or Br atom with a sec. amine (III) where R is (1-6)C lower alkyl gp. The reaction is carried out in a solvent such as toluene at between 60 and 140 deg.C and in the presence of a carbonate or bicarbonate. The inorganic salts are finally sepd. by pptn. in water or filtration, the prod. of general formula (I) being isolated by vacuum distn.</p>
申请公布号 ES8601128(A1) 申请公布日期 1986.02.16
申请号 ES19510005379 申请日期 1984.11.26
申请人 FORDONAL, S.A. 发明人
分类号 A61K31/40;C07D207/27;(IPC1-7):C07D207/27 主分类号 A61K31/40
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