发明名称 Naphthalene anti-psoriatic agents
摘要 <p>A compsn. for treating psoriasis comprises a pharmaceutically acceptable non-toxic carrier and naphthalene derivs. of formula (I) (R1=1-12C alkoxy, 1-12C alkylthio, phenoxy or phenylthio opt. substd. by 1 or 2 of 1-4C alkyl, 1-4C alkoxy or halo; R2=H, 1-6C alkyl, phenyl or phenylalkyl, opt. substd. by 1 or 2 of 1-4C alkyl, 1-4C alkoxy or halo; R3=1-6C alkyl, 1-6C alkoxy or halo; m=0-2 or R3 is opt. substd. phenyl, opt. substd. phenyl lower alkyl, opt. substd. phenyl lower alkoxy, amino, lower alkylamino, lower dialkylamino, CN or S(O)nR where R is 1-6C alkyl, opt. substd. phenyl, opt. substd. phenyl lower alkyl or heterocyclic aryl of 3-9 ring atoms contg. 1 or 2 of N, O or S; the heterocyclic aryl is opt. substd. by 1 or more of lower alkyl, lower alkoxy, halo or CN and the pharmaceutically acceptable acid addn. salts thereof; and m=1 and n=0-2. W=1-7C alkyl, phenyl or benzyl opt. substd. with 1-2 of 1-4C alkyl, 1-4C alkoxy or halo).</p>
申请公布号 ES8601089(A1) 申请公布日期 1986.02.16
申请号 ES19660005398 申请日期 1985.01.25
申请人 SYNTEX (U.S.A.) INC. 发明人
分类号 C07D521/00;A61K31/215;A61K31/22;A61K31/235;A61K31/275;A61P17/00;C07C46/00;C07C50/10;C07C50/14;C07C50/24;C07C50/32;C07C67/00;C07C69/017;C07C69/157;C07C69/78;C07C213/00;C07C225/36;C07C253/00;C07C255/55;C07C313/00;C07C317/22;C07C323/21;C07C323/22;C07C323/62;C07D213/64;C07D213/89;C07D239/38;C07D333/64;(IPC1-7):C07C50/12;C07C13/48;A61K31/12 主分类号 C07D521/00
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