| 摘要 |
<p>The known cleaning of contact lenses by sequential soaking in aq. proteolytic enzyme (I) then disinfecting is improved by heating the lenses in the aq. (I) soln. to achieve cleaning and disinfection in one step. - Uses as (I), papain, pancreatin, or a protease (amylase etc.) which may be derived from Bacillus, Streptomyces, or Aspergillus spp. (esp. B. subtilis). - Heating is to 60-100 esp. 65-85 deg. C for up to 60 min. Prepd. solns. also contain tonicity agents (esp. made isotonic), 0.00001-0.5 % esp. 0.0001-0.1% by wt. preservatives (thimerosal, sorbic acid, etc.), 0.1-2% by wt. chelating agents (esp. EDTA or di-Na salt), 0.5-2.5% esp. 0.1-1.5% by wt. buffers, and up to 15% by wt. surfactants (polycarbonate 20, polyoxyethylene (4) stearate etc.).</p> |
