发明名称 Benzimidazole derivs. prepn.
摘要 <p>The process comprises reacting a cpd. of formula (II) with a cpd. of formula (R1)2O or R1-Hal in the presence of an organic base to give a cpd. of formula (I) where m = 0-3, R is a 1-6C alkyl gp., a 3-5C alkenyl gp., alkynyl gp. or a substd., benzyl gp., R1 is a 1-4C alkaneyl etc., R2 is H, halogen or methyl gp., R3 is H, halogen or methyl gp., X is O or S, Y is halogen, 1-4C alkyl gp., alkoxy gp., etc. The organic base can be alkali metal hydroxides or organic bases such as pyridine and tert. amines in an inert solvent, the reaction temp. being -20 to +100 deg. C.</p>
申请公布号 ES8601150(A3) 申请公布日期 1986.02.16
申请号 ES19860005395 申请日期 1985.01.16
申请人 CIBA-GEIGY AG 发明人
分类号 A61K31/415;C07D235/28;(IPC1-7):C07D235/28 主分类号 A61K31/415
代理机构 代理人
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