MEDICINAL PREPARATION HAVING ANTINICOTINE EFFECT AND METHOD FOR OBTENTION THEREOF

摘要

A pharmaceutical preparation, in a chewing gum carrier, possessing an antinitocine effect which comprises a biologically resorbable polymeric vehicle containing a cation-exchange group and modified thereat by an antinicotine-action action alkaloid in the following proportions thereof, percent by mass: antinitocine-action alkaloid 2.5-40.0 polymeric vehicle the balance. The method of producing the preparation comprises reacting a biologically resorbable polymeric vehicle containing a cation-exchange group with an antinicotine-action alkaloid in an aqueo-organic medium at a volume ratio of the aqueous and organic phases of 1-15:1-24 respectively and at a temperature within the range of from 8 DEG to 22 DEG C.