| 摘要 |
PURPOSE:To provide the titled composition containing a non-steroidal anti-inflammatory analgesic, its salt, or their derivative, and a nicotinic acid ester, and having excellent transcutaneous absorbability. CONSTITUTION:The objective anti-inflammatory analgesic drug for external use having excellent transcutaneous absorbability can be prepared by compounding (A) 100pts.wt. of a non-steroidal anti-inflammatory analgesic (exclusing salicyclic acid derivative, diclofenac and indomethacin: e.g. phenylacetic acid derivative such as alkofenac, indoleacetic acid derivative such as sulindac, propionic acid derivative such as ibuprofen, anthranylic acid derivative such as flufenamic acid, pyrazolone derivative such as phenylbutazone, oxicam-type acidic agent such as pyroxicam, or non-acidic agent such as tinoridine) with (B) >=5pts.wt., preferably >=10pts.wt. of a nicotinic acid ester. In the case of the treatment of the pain of shoulder discomfort, rheumatism, etc., it is applied continuously for 1-2 weeks at a dose of 1g/dose, and 3-4 doses daily. |
