发明名称 PROCESS FOR PREPARING NOVEL CEPHALOSPORIN DERIVATIVES AND OF PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME
摘要 <p>Novel cephalosporin derivatives of the formula <IMAGE> wherein R<1> is hydrogen or a conventional amino-protecting group, and R<2> is a straight or branched alkyl group containing from 1 to 4 carbon atoms, allyl, 2- butenyl or 3-butenyl, or is a group <IMAGE> wherein R<3> and R<4> each are independently hydrogen, methyl or ethyl, or R<3> and R<4>, taken together with the carbon atom to which they are attached, may be a cycloalkylidene ring containing from 3 to 5 carbon atoms, and nontoxic pharmaceutically acceptable salts, physiologically hydrolyzable esters and solvates thereof exhibit potent antibacterial activity and can be incorporated into pharmaceutical compositions.</p>
申请公布号 PT76330(B) 申请公布日期 1986.02.04
申请号 PT19830076330 申请日期 1983.03.03
申请人 BRISTOL MYERS COMPANY 发明人 SHIMPEI ABURAKI;HAJIME KAMACHI;YUKIO NARITA;JUN OKUMURA;TAKAYUKI NAITO
分类号 C07D501/46;A61K;A61K31/545;A61K31/546;C07D;C07D417/04;C07D501/00;C07D501/04;C07D501/36;C07D501/38;C07D501/44;C07D501/56;(IPC1-7):C07D501/46 主分类号 C07D501/46
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