发明名称 |
A GENETIC ENGINEERING PROCESS FOR THE PREPARATION OF HUMAN INTERLEUKIN-2 AND MEANS FOR CARRYING OUT THIS PROCESS |
摘要 |
A synthetic DNA sequence can be used to obtain human interleukin-2 in a genetic engineering process. The gene is advantageously synthesised in the form of a plurality of fragments which are ligated enzymatically to give larger part-sequences which are incorporated into hybrid plasmids and amplified in host organisms. The part-sequences are reisolated and then combined to give the complete gene and incorporated into a hybrid plasmid, and the latter is expressed in a host organism. |
申请公布号 |
ZA8504031(B) |
申请公布日期 |
1986.01.29 |
申请号 |
ZA19850004031 |
申请日期 |
1985.05.28 |
申请人 |
HOECHST AKTIENGESELLSCHAFT |
发明人 |
JOACHIM ENGELS;FRIEDRICH WENGENMAYER;ERNST-LUDWIG WINNACKER;HIROSHI OKAZAKI;EUGEN UHLMANN;HUBERT MUELLNER;RONALD MERTZ |
分类号 |
C12N15/09;A61K38/00;A61K38/16;C07H21/04;C07K14/00;C07K14/52;C07K14/54;C07K14/55;C12N1/20;C12P21/00;C12P21/02;C12R1/19 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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