1,4-DIHYDROPYRIDINE DERIVATIVES AND PROCESSES FOR PREPARING THE SAME

摘要

Novel 1,4-dihydropyridine derivatives or the pharmacologically acceptable salts thereof represented by the following general formula (I), and process for preparing the same. where R<1> is dialkoxyalkyl, formyl, formylalkyl, or hydroxyalkyl; R<2> represents alkoxyalkyl, alkenyloxyalkyl, aryloxyalkyl, or aralkyloxyalkyl; R<3> denotes alkyl, haloalkyl, alkoxyalk, alkenyloxyalkyl, aryloxyalkyl, aralkyloxyalkyl, or N,N-disubstituted aminoalkyl (the substituents are the same or different alkyl, aralkyl, or aryl); R<4> is alkyl, dialkoxyalkyl, formyl, formylalkyl, or hydroxyalkyl; and R<5> is ortho-, meta-, or paranitro. The compounds of the present invention possess vaso-dilation activities and hypotensive activities, and are expected to be highly useful medicines for the blood circulatory system.