<p>An anti-amnestic agent which comprises as an active ingredient thereof at least one prolinal derivative of the general formula: <IMAGE> wherein A is a protective groups for amino group in the field of amino acid chemistry and X is a residue of an amino acid, in a pharmacologically active amount together with an exipient. This agent is less toxic and can be safely administered to patients orally or intravenously for the remedy of memory disorder.</p>