发明名称 Dicarbamates
摘要 Novel pyrimidinedicarbamates of the formula <IMAGE> I wherein R is lower alkyl or (lower alkyloxy)-(lower alkyl) and X is a leaving group, can be manufactured by carbamoylating the corresponding free diamines. They are valuable intermediates and can be used, for example, for the manufacture of corresponding oxadiazolopyrimidines of the formula <IMAGE> II and pharmaceutically acceptable salts thereof. The latter have valuable long-lasting vasodilating and/or bloodpressure lowering properties and are accordingly suitable especially for the treatment of vascular-conditioned hypertensions or as vasodilators in the case of peripheral blood supply disorders.
申请公布号 US4565869(A) 申请公布日期 1986.01.21
申请号 US19830472696 申请日期 1983.03.07
申请人 HOFFMANN-LA ROCHE INC. 发明人 IMFELD, MARQUARD;RAMUZ, HENRI;VOGT, PETER;MULLER, JEAN-CLAUDE
分类号 C07D239/48;C07D401/04;C07D498/04;(IPC1-7):C07D239/48 主分类号 C07D239/48
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