摘要 |
<p>Crystalline, optically pure dipilocarpinium pamoate (II) having m.pt >111 degrees C and X-ray max corresp. to both theta (theta) equal to 7.4, 9.0, 11.9 and 19.7 degrees is claimed. New dipilocarpinium pamoate ketone solvate, (A), in which mol ratio ketone: dipilocarpinium pamoate is 1:1, contains a ketone portion having formula R1-CO-R1 (I) (where R1 is 1-3C alkyl). (II) is prepd. by sepg. ketone (I) from dipilocarpinium pamoate ketone solvate (A). Dipilocarpinium pamoate is used in treatment of glaucoma.</p> |