| 摘要 |
The carbapenems of the formula <IMAGE> in which R<1> is lower alkyl, aryl or aryl-lower-alkyl, R<2> is carboxyl or 5-tetrazolyl, R<3> is hydrogen or a substituent customary for position 6 of carbapenems, and R<4> is hydrogen or a substituent customary for position 3 of carbapenems, conventional esters, which can be hydrolysed under physiological conditions, of compounds of the formula I in which R<2> is carboxyl, and pharmaceutically acceptable salts thereof and hydrates of these substances have valuable antibiotic properties and can be used for controlling or preventing infectious diseases. |
