| 摘要 |
<p>A-21978C cyclic peptide derivatives of the formula <IMAGE> 1 wherein R is hydrogen, a specified aminoacyl or N-alkanoylaminoacyl group, 8-methyldecanoyl, 10-methyldodecanoyl, 10-methylundecanoyl, the specific C10-alkanoyl group of A-21978C0 or the specific C12-alkanoyl groups of A-21978C factors C4 and C5 or an amino-protecting group; and R1 is hydrogen, an amino-protecting group, or a specified aminoacyl or N-alkanoylaminoacyl group; provided that, when R is other than aminoacyl or N-alkanoylaminoacyl, R1 must be aminoacyl or N-alkanoylaminoacyl; and, when R1 is an amino-protecting group, R must be aminoacyl or N-alkanoylaminoacyl; and the salts thereof, are useful as antibacterial agents or as intermediates to antibacterial agents.</p> |
