发明名称 |
METHOD OF PRODUCING INTERNAL SALTS OF NAPHTHALENYLTHIAZOLE DERIVATIVES |
摘要 |
Disclosed herein are new aldose reductase inhibitors of the formula <IMAGE> wherein R is <IMAGE> wherein R1 is lower alkyl; R2 is halo and R3 is hydrogen, or R2 and R3 each is a substituent at positions 3, 4, 5 or 6 of the naphthalene ring selected from the group consisting of lower alkoxy, trihalomethyl, and halo; and R4 is lower alkyl. The derivatives are useful for treating or preventing diabetic complications. |
申请公布号 |
SU1205767(A3) |
申请公布日期 |
1986.01.15 |
申请号 |
SU19833645598 |
申请日期 |
1983.09.20 |
申请人 |
AYERST MCKENNA & HARRISON |
发明人 |
KAZIMIR SESTANI,CA;FRANCHESKO BELLINI,CA |
分类号 |
C07D277/20;A61K31/425;A61K31/426;A61P3/08;A61P3/10;C07D277/34 |
主分类号 |
C07D277/20 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|