发明名称 TREATMENT OF CARDIAC FAILURE USING IMIDAZOLECARBOXYLIC ACID DERIVATIVES
摘要 The use of novel imidazolecarboxylic acid derivatives of the following general structure which are useful as antihypertensives, cardiotonics and antithrombotics <IMAGE> wherein Q and T are an oxygen or sulfur atom; R is hydrogen, lower alkyl, lower alkylcarbonyl or benzoyl; R1 is hydrogen or -CH(R3)R4; R2 is lower alkoxy, phenoxy or phenoxy substituted at the ortho, meta, or para position with lower alkyl, lower alkoxy, hydroxy, halogen, trifluoromethyl, lower alkylthio, lower alkylsulfone, or lower alkylsulfoxide; R3 is hydrogen or lower alkyl; R4 is hydrogen, hydroxy, lower alkoxy, lower alkylcarbonyl, -ONO2 or halogen; and their pharmaceutically acceptable salts thereof.
申请公布号 PH19153(A) 申请公布日期 1986.01.15
申请号 PH19780000280 申请日期 1980.11.02
申请人 MERRELL DOW PHARMACEUTICALS INC. 发明人 RICHARD ANSELM SCHNETTLER;RICHARD CYRUS DAGE;JOHANN MARTIN GRISAR
分类号 C07D233/70;A61K31/415;A61P25/02;C07D233/90 主分类号 C07D233/70
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