发明名称 Peptide derivatives and their use as substrates for quantitative determination of enzymes
摘要 Peptide derivatives of the formula: <IMAGE> in which R<1> is a substituted amino group which can be enzymatically eliminated to form a coloured or fluorescent compound R<1>-H. The said peptide derivatives are used for the quantitative determination of the enzyme C1-esterase. The determination is carried out by reacting a medium which contains C1-esterase, or in which the latter is produced or consumed, with one of the above-defined peptide derivatives and by measuring the amount of the cleavage product R<1>-H which is liberated per unit time by the catalytic hydrolytic action of the said enzyme on the peptide derivative, by photometric, spectrophotometric, fluorescent spectrophotometric or electrochemical methods.
申请公布号 CH653688(A5) 申请公布日期 1986.01.15
申请号 CH19830003051 申请日期 1983.06.03
申请人 PENTAPHARM AG 发明人 SVENDSEN, LARS-GUNDRO
分类号 C07K5/04;C07K5/08;C07K5/09;C07K5/10;C07K5/103;C07K5/107;C12Q1/44;G01N33/52;(IPC1-7):C07K5/04;G01N33/68 主分类号 C07K5/04
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