发明名称 |
GUAIACIL ESTERI DI DERIVATI DELLO ACIDO MERCAPTOPROPIONICO PROCEDIMENTO PER LA LORO PREPARAZIONE E LORO USO TERAPEUTICO |
摘要 |
<p>Guaiacol esters of alpha- and beta-mercaptopropionyl alanine and of alpha- and beta-mercaptopropionyl glycine having formulae: …<CHEM>… wherein R is hydrogen or methyl and Y is hydrogen or an acyl radical (acetyl, benzoyl or methoxycarbonyl). …<??>Pharmaceutical compositions containing these guaiacol esters have mucolytic activity. …<??>The process for manufacturing these guaiacol esters comprises preparing in a known per se manner a sulhydryl group-containing intermediate wherein the sulfhydryl is protected by a trityl or p-methoxybenzyl group, and removing the protective group under acid conditions.</p> |
申请公布号 |
IT1111384(B) |
申请公布日期 |
1986.01.13 |
申请号 |
IT19780052417 |
申请日期 |
1978.12.21 |
申请人 |
SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE SPA |
发明人 |
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分类号 |
A61K31/24;A61K;A61K31/095;A61K31/10;A61K31/215;A61K31/22;A61K31/265;A61P11/10;C07C;C07C67/00;C07C69/017;C07C313/00;C07C319/20;C07C323/60;C07C325/00;C07C327/06;C07C327/20;C07C327/22;C07C327/32;(IPC1-7):A61K/ |
主分类号 |
A61K31/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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