PROCEDIMIENTO DE PREPARACION DE 3-TRIFLUOROMETIL-4'-HIDROXI--A-ETIL-BENZOL

摘要

The invention relates to the preparation of 3-trifluoromethyl- and 2,5-dimethyl-4'-hydroxy- alpha -ethyl-benzhydrol. Both compounds have so far been described only as metabolites of corresponding benzhydrol derivatives containing no hydroxyl group. Neither their physico-chemical characteristics nor their manufacturing processes have been disclosed in the known publications. 3-Trifluoromethyl- and 2,5-dimethyl-4'-hydroxy- alpha -ethyl-benzhydrol are suitable for the treatment of acute ethanolic intoxication. Accordingly, another aspect of the invention is a pharmaceutical composition containing one of these compounds as active ingredient.