摘要 |
<p>PT--81639 A 2,3-Dihydro 3-phenyl 2-oxo 1H-indole 1-acetamide (I) is made from phenyl acetic acid phenylhydrazide which is cyclised to the corresp. oxoindole by heating in presence of a metal oxide. The oxoindole is alkylated with ethyl chloracetate in basic medium, and the prod. subjected to ammonlysis with concn. ammonium hydroxide to the corresp. primary amide (I)</p> |