发明名称 PROCESS FOR PREPARING NEW IMIDAZOISOQUINOLINE DIONES
摘要 Compounds of the formula <IMAGE> wherein R1 is lower alkyl; phenyl-lower alkyl; cycloalkyl of 3 to 6 carbon atoms; phenyl; mono- or di-substituted phenyl, where the substituents, which may be identical to or different from each other, are each halogen, hydroxyl, methoxy, methylmercapto, methylsulfinyl, methylsulfonyl or benzyloxy; and A is hydrogen or <IMAGE> where R2 is hydrogen or lower alkyl; R3 is lower alkyl or dimethoxyphenyl-lower alkyl; or R2 and R3, together with each other and the nitrogen atom to which they are attached, are piperidino, morpholino or N'-lower alkyl-piperazino; and n is 2 or 3; and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as cardiotonics, hypotensives, antithrombotics and antiarrhythmics.
申请公布号 YU40340(B) 申请公布日期 1985.12.31
申请号 YU19780001747 申请日期 1978.07.20
申请人 DR KARL THOMAE GMBH 发明人 AUSTEL V.;KUTTER E.;HEIDER J.;EBERLEIN W.;KOBINGER W.;LILLIE C.;DIEDERN W.
分类号 A61K31/47;A61K31/4745;A61K31/495;A61K31/535;A61P7/02;A61P9/04;A61P9/06;A61P9/08;A61P9/10;A61P9/12;A61P25/20;C07D217/24;C07D471/04;(IPC1-7):C07D471/04 主分类号 A61K31/47
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