| 摘要 |
Ethylenediamine, mono-or diethanolamine salts of N-(2-pyridyl) -2- methyl-hydroxy-2H-1,2-benzothiazone-3-carboxamide 1,1-dioxide (I) were prepd. Thus, H2NCH2CH2NH2 was added to (I) in water and the mixt. was heated for 30min. in a water bath. The resulting soln., yellow color, was evaporated in vaccum and triturated by a chloroform/ethylacetate solvent system to give the ethylenediamine salts of (I). (I) are used in antiarthritic compsn. for treatment of warm-blooded animals.
|
