| 摘要 |
2-Oxindole-1-carboxamides of the formula: …<CHEM>… and their pharmaceutically acceptable base-salts, where X and Y are certain optional substituents or can be taken together to form certain ring structures; and R<1> is alkyl, cycloalkyl, cycloalkenyl, optionally substituted phenyl, optionally substituted phenylalkyl, optionally substituted phenoxyalkyl, (thiophenoxy) alkyl, naphthyl, bicyclo [2.2.1]heptan-2-yl, bicyclo [2.2.1]hept-5-en-2-yl or a group of the formula -(CH2)n-Q-R<0> where n is 0, 1 or 2, Q is a divalent radical which is a specified heterocycle, and R<0> is H or alkyl. …<??>The compounds are useful as analgesic and anti-inflammatory agents. …<??>Also covered are certain intermediates useful in the preparation of the compounds (I), these intermediates having H in place of -COR<1>. |
