Polyprenyl compound, process of producing it and pharmaceutical use.

摘要

A novel polyprenyl compound is identified with the formula and useful for a pharmaceutical drug.
<Chemistry id="chema01" num="0001"><Image id="ia01" he="13" wi="39" file="IMGA0001.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>wherein X represents a group of the formula:
<Chemistry id="chema02" num="0002"><Image id="ia02" he="16" wi="39" file="IMGA0002.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>(wherein R' and R<Sup>2</Sup>, which may be the same or different, represent each a hydrogen atom, a lower alkyl group, a hydroxyalkyl group, or a lower alkenyl group); a group of the formula
<Chemistry id="chema03" num="0003"><Image id="ia03" he="13" wi="32" file="IMGA0003.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>(wherein A including the nitrogen atom shown represents a ring containing nitrogen and oxygen atoms); or a group of the formula:
<Chemistry id="chema04" num="0004"><Image id="ia04" he="24" wi="45" file="IMGA0004.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>

(wherein R<Sup>3</Sup> represents a hydrogen atom or a lower alkyl group. and R<Sup>4</Sup> represents a lower alkyl group); Y represents a group of the formula:
<Chemistry id="chema05" num="0005"><Image id="ia05" he="17" wi="24" file="IMGA0005.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>or a group of the formula:
<Chemistry id="chema06" num="0006"><Image id="ia06" he="12" wi="46" file="IMGA0006.TIF" imgContent="chem" imgFormat="TIFF" inline="no" /></Chemistry>(wherein R<Sup>5</Sup> represents a hydrogen atom or a lower alkyl groupi, and n represents an integer of from 2 to 5. Also a process for producing the polyprenyl compound is disclosed.